IMM events :
The Institut de Microbiologie de la Méditerranée (IMM) organises scientific seminars for researchers every Friday at 11.30am.
These seminars are announced in the Institute’s diary.
The seminar organising committee is made up of :
– Bénédicte BURLAT, researcher at BIP
– Isabelle IMBERT, teacher-researcher at LISM
– Vladimir PELICIC, researcher at the LCB
– Hugo BISIO, researcher at IGS
Seminar information :
– Frequency: Every Friday
– Time: 11.30 a.m.
– Accessibility: These events are not open to the general public. For open events, please consult the public events page.
List of Seminars:
Below is the list of scientific seminars scheduled for the coming month.
If you have any questions or require further information, please do not hesitate to contact the organising committee: seminaires@imm.cnrs.fr
- This event has passed.
Jean-Yves MATROULE
4 April/11h30 - 12h30
Jean-Yves Matroule (URBM – University of Namur – Belgium)
“How to handle a Double-Edged Sword: Lessons from a Free-Living Bacterial Model”.
The Great Oxygenation Event not only increased atmospheric oxygen but also enhanced copper (Cu) solubility and bioavailability, driving its integration into key metalloproteins involved in oxygen-dependent processes such as superoxide dismutase and cytochrome C oxidase. However, this surge in soluble Cu came with toxic consequences at high concentrations, including reactive oxygen species (ROS) generation, metal displacement, and proteotoxicity.
To survive in this new Cu-rich environment, bacteria evolved resistance mechanisms, including copper chelation, detoxification, and efflux. These systems have been well-characterized in Escherichia coli and certain pathogens including Pseudomonas _aeruginosa_and Salmonella that encounter copper during infection.
Best known as a model organism for cell cycle regulation, the aquatic free-living bacterium Caulobacter vibroides harbors a remarkable array of genes linked to environmental stress responses. Over the past decade, studies from our group and others have revealed that Caulobacter employs unconventional copper resistance strategies that go beyond the canonical pathways established in classical bacterial models. These findings expand our understanding of bacterial adaptation to metal stress and provide new perspectives on microbial resilience in dynamic environments.