IMM events :
The Institut de Microbiologie de la Méditerranée (IMM) organises scientific seminars for researchers every Friday at 11.30am.
These seminars are announced in the Institute’s diary.
The seminar organising committee is made up of :
– Bénédicte BURLAT, researcher at BIP
– Isabelle IMBERT, teacher-researcher at LISM
– Vladimir PELICIC, researcher at the LCB
– Hugo BISIO, researcher at IGS
Seminar information :
– Frequency: Every Friday
– Time: 11.30 a.m.
– Accessibility: These events are not open to the general public. For open events, please consult the public events page.
List of Seminars:
Below is the list of scientific seminars scheduled for the coming month.
If you have any questions or require further information, please do not hesitate to contact the organising committee: seminaires@imm.cnrs.fr
The genetics of natural populations of Escherichia coli from Escherich to the present day
Erick Denamur (IAME , Paris-Cité)
The genetics of natural populations of Escherichia coli from Escherich to the present day
Having been awarded the Nobel Prize for Medicine for his discovery of the lactose operon in E. coli, Jacques Monod declares that “what is true for E. coli is also true for the elephant”. E. coli K-12 is indeed an extraordinary model organism for studying the basic principles conserved in living organisms in biochemistry, molecular biology and genetics. But is what is true for E. coli K-12 also true for all natural isolates of E. coli?
We’ll take a historical perspective to answer this question. As early as 1886, Theodor Escherich, a 29-year-old German pediatrician, posed the problem: how to explain the fact that E. coli is both a commensal in the digestive tract of mammals and birds and a formidable intestinal and extraintestinal pathogen.
I will present the highlights of 30 years of research in my laboratory on the subject.
Publications
Teaching journals
Denamur E, Clermont O, Bonacorsi S, Gordon D. The population genetics of pathogenic Escherichia coli. Nat Rev Microbiol. 2021 Jan;19(1):37-54.
Tenaillon O, Skurnik D, Picard B, Denamur E. The population genetics of commensal Escherichia coli. Nat Rev Microbiol. 2010 Mar;8(3):207-17.
Denamur E, Matic I. Evolution of mutation rates in bacteria. Mol Microbiol. 2006 May;60(4):820-7.
Full list
https://scholar.google.com/citations?user=CWKJ2C8AAAAJ&hl=en
Invited by A. Battesti (LCB)