IMM events :

The Institut de Microbiologie de la Méditerranée (IMM) organises scientific seminars for researchers every Friday at 11.30am.
These seminars are announced in the Institute’s diary.

The seminar organising committee is made up of :
– Bénédicte BURLAT, researcher at BIP
– Isabelle IMBERT, teacher-researcher at LISM
– Vladimir PELICIC, researcher at the LCB
– Hugo BISIO, researcher at IGS

Seminar information :
– Frequency: Every Friday
– Time: 11.30 a.m.
– Accessibility: These events are not open to the general public. For open events, please consult the public events page.

List of Seminars:
Below is the list of scientific seminars scheduled for the coming month.
If you have any questions or require further information, please do not hesitate to contact the organising committee: seminaires@imm.cnrs.fr

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Khaled A. SELIM

25 April/11h30 - 12h30

Khaled A. Selim (Microbial Biochemistry Group, Institute of Photoautotrophic Microbiology, University of Düsseldorf, Universitätsstr. 1, 40225 Düsseldorf, Germany)

“PII signaling superfamily in cyanobacterial: a new paradigm for controlling cellular homeostasis”.

Because of their photosynthesis-dependent lifestyle, cyanobacteria evolved sophisticated regulatory mechanisms to adapt to oscillating day-night metabolic changes, which is very crucial for their multicellularity lifestyle. How they coordinate the metabolic switch between autotrophic and heterotrophic metabolism in light/dark cycles is poorly understood. Members of the PII signaling superfamily adeptly monitor and synchronize the cell’s carbon, nitrogen, energy, redox, and diurnal states, primarily by binding interdependently to adenyl-nucleotides, including charged nucleotides (ATP, ADP, and AMP) and second messengers such as cAMP, and c-di-AMP. These proteins also undergo a variety of posttranslational modifications, such as phosphorylation, adenylation, uridylation, carboxylation, and disulfide bond formation, which further provide cues on the metabolic state of the cell. Serving as precise metabolic sensors, PII superfamily proteins transmit this information to diverse cellular targets, establishing dynamic regulatory assemblies that fine-tune cellular homeostasis. This highlights PII signaling superfamily as a central switch-point in cyanobacterial cell physiology.

Invited by A. Latifi (LCB)

Details

Date:
25 April
Time:
11h30 - 12h30
Event Category: