Nuclear Magnetic Resonance

Picto Résonance magnétique nucléaire Plateforme IMM

The NMR platform offers state-of-the-art equipment for the structural characterization of molecules in solution, from metabolites to macromolecular complexes. Users benefit from both technical expertise and equipment for analyses in the fields of chemistry, metabolomics and biology.

The platform is equipped with a BRUKER 600 MHz spectrometer, a cryoprobe and a latest-generation electronic console (Avance NEO). This is the most powerful NMR equipment in the PACA region, enabling the analysis of molecules in small quantities or complex mixtures.

Applications range from the structural determination of small molecules (natural or synthetic substances) and macromolecules (proteins, nucleic acids) to the dynamic study of complex systems, for example through kinetic monitoring.

Scientific Director: Dr Latifa Elantak.

Olivier BORNET
Technical manager

Contact the platform

The platform's areas of expertise
Nuclear Magnetic Resonance

Analysis and control of the structure of biological or chemical molecules

Metabolomic analysis of biological systems

Identification and characterization of molecular interactions

Reaction kinetics (enzymatic, polymerization, functionalization)

The platform's areas of expertise
Nuclear Magnetic Resonance

Analysis and control of the structure of biological or chemical molecules

Metabolomic analysis of biological systems

Identification and characterization of molecular interactions

Reaction kinetics (enzymatic, polymerization, functionalization)

Services offered by the
Nuclear Magnetic Resonance platform

R&D

Structural analysis of molecules, Purity analysis and quantification, Chemical kinetics and
molecular dynamics, Protein-ligand interaction studies, Analysis of complex mixtures,
Support for stability studies, Technical assistance and training

Services

Routine NMR analysis, Customized NMR analysis service, Quality control, Compound identification, Advanced structural analysis, Process development support, Stability and degradation studies

Consulting and training

Practical training in the use of NMR equipment for technicians or researchers. Training in NMR spectra interpretation for users requiring in-depth expertise. Customized technical assistance in setting up specific NMR protocols or solving complex analytical problems.

  • Superconducting magnet
  • AVANCE NEO

Featured publications

2024

Pre-B cell receptor acts as a selectivity switch for galectin-1 at the pre-B cell surface. Cell Reports. 2024 Aug 27;43(8):114541. doi: 10.1016/j.celrep.2024.114541. Epub 2024 Jul 25. PMID: 39058594.

Touarin P, Serrano B, Courbois A, Bornet O, Chen Q, Scott LG, Williamson JR, Sebban-Kreuzer C, Mancini SJC, Elantak L.

2024

A molecular switch controls assembly of bacterial focal adhesions. Science Advances. 2024 May 31;10(22):eadn2789. doi: 10.1126/sciadv.adn2789. Epub 2024 May 29. PMID: 38809974; PMCID:

Attia B, My L, Castaing JP, Dinet C, Le Guenno H, Schmidt V, Espinosa L, Anantharaman V, Aravind L, Sebban-Kreuzer C, Nouailler M, Bornet O, Viollier P, Elantak L, Mignot T.

2024

Monitoring galactolipid digestion and simultaneous changes in lipid-bile salt micellar organization by real-time NMR spectroscopy. Chemistry and Physics of Lipids. 2024 Jan;258:105361. doi: 10.1016/j.chemphyslip.2023.105361. Epub 2023 Nov 21. PMID: 37981224.

Sahaka M, Bornet O, Marchand A, Lafont D, Gontero B, Carrière F, Launay H.

2021

Launay H, Shao H, Bornet O, Cantrelle FX, Lebrun R, Receveur-Brechot V, Gontero B.

2020

Roblin C, Chiumento S, Bornet O, Nouailler M, Müller CS, Jeannot K, Basset C, Kieffer-Jaquinod S, Couté Y, Torelli S, Le Pape L, Schünemann V, Olleik H, De La Villeon B, Sockeel P, Di Pasquale E, Nicoletti C, Vidal N, Poljak L, Iranzo O, Giardina T, Fons M, Devillard E, Polard P, Maresca M, Perrier J, Atta M, Guerlesquin F, Lafond M, Duarte V.

All our publications

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Do you have a question about IMM's Nuclear Magnetic Resonance platform? If you have any questions about our services or training courses, please contact our team.

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